Postdoctoral Research Associate

Overview

Attention human B cell immunologists and / or genetics / genomics expert : the at the Benaroya Research Institute has an open postdoc position for a funded project pertaining to lupus genetic risk .

The Ray lab intersects immunology and genetics to define genetic mechanisms that drive risk for autoimmune diseases such as lupus, multiple sclerosis, type 1 diabetes, and rheumatoid arthritis, among others.

The lab performs functional genomic approaches in immune cells to identify genetic variants, genes, and cis-regulatory regions that likely promote disease risk and clarifies their mechanisms using human and mouse cellular and molecular immunological approaches.

Dr. Ray has affiliate appointments at the University of Washington Departments of Immunology and Genome Sciences.

Responsibilities

B cell immunologist and / or genetics / genomics expert : will focus on performing high throughput CRISPR screens in human primary B cells from lupus patients and healthy controls to define genetic variants, cis-regulatory regions, and genes that drive lupus and their mechanisms.

Other current projects in the Ray Lab focus on :

• Massively parallel prioritization of disease-associated genetic variants in T cells.
• Mapping enhancers that control T cell function and their target genes at steady state and in infection and autoimmunity using bulk and single cell CRISPR screens.
• In vivo enhancer screening in autoimmune mouse models.
• In vivo CRISPR screens of genes that drive pathogenic cells in lupus nephritis.

Qualifications

We are seeking highly motivated yet team-oriented individuals with an aptitude for developing and / or applying skills in genetics, genomics, immunology, or bioinformatics.

The individuals we are seeking will hold MD, PhD, or MD / PhD degrees in immunology, genetics, or genome sciences. Expertise in human primary B or T cell biology and culture techniques and / or in genomic and statistical approaches are highly preferred.

Furthermore, training opportunities will be provided in bioinformatics or immunology as needed.

Interested applicants should email with their CV and a statement of interest.

Compensation

$67,744 - $75,112 per year

Benefits

• Medical, dental, vision hardware insurance
• Flexible spending accounts : health care, dependent care, commuter
• Short and long-term disability and life and AD&D insurance
• 403(b) retirement plan with matching funds after one year of employment
• PTO : 13 holidays, three weeks of vacation and two weeks of sick leave per year
• Employee assistance program
• Educational assistance program
• Subsidized bus pass
• YMCA rebate and other fitness club discounts
• Voluntary benefits, e.g., pet insurance, accident, critical illness, identify theft
• See for benefit details

About Us

Benaroya Research Institute (BRI) has a bold mission : To predict, prevent, reverse and cure immune system diseases, from autoimmune disease to cancer to COVID-19.

We examine the immune system in both health and disease to understand how disorders start and how to rebalance the immune system back to health.

Equipped with innovative tools and robust biorepositories, our team chips away at the biggest mysteries behind these conditions to work toward our vision of a healthy immune system for everyone.

BRI is a world-renowned independent nonprofit research institute affiliated with Virginia Mason Franciscan Health and based in Seattle.

We collaborate with clinicians to accelerate the path from innovative lab discoveries to life-changing patient care.

At BRI, each role is valued and an important contributor to our vision and mission. BRI is committed to a safe, caring and diverse workplace;

as well as to taking action to further our commitments to foster inclusion, equity and belonging so employees feel comfortable bringing their full selves to work.

Consider making a difference by joining our team. Because together, we are powering possibility.

To learn more, visit and connect with us on , , , , and .

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, citizenship, disability or protected veteran status.

If you need assistance completing the application process, please contact Human Resources at 206-342-6972 or email

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