Role : Analytical Chemist
Location : San Francisco, CA
Pay : $110-160,000
Responsibilities :
- Design and execute experiments to fully characterize the oligonucleotide drug substance and drug product materials.
- Demonstrate proficiency with analytical characterization techniques mass spectrometry, liquid chromatography, UV / Fluorescence, and electrophoresis)
- Ability to independently conceive, develop, execute, and then implement novel / advanced scientific techniques. Holistic thinker for analytical packages.
- Report at project team meetings, write analytical development reports, provide recommendations to management.
- Manage and support junior team members.
- Collaborate with internal and external manufacturing partners to develop robust analytical methods.
- Participate in multidisciplinary teams including Biology (in vitro and in vivo pharmacology), and Chemistry (production, analytical sciences, and platform chemistry groups) Present results through team meetings and recommendations to management.
- Deliver innovative solutions using a diversity of thought and experiences.
- Ensure the quality of each delivered entity.
- Maintain lab notebooks, report data with analysis of results in presentations and / or written reports to the scientific team.
Required Qualifications
- The level of this position will depend on education and experience qualifications :
- Scientist PhD in analytical, organic chemistry or a related discipline with minimum of 4 years of direct experience in oligonucleotide analysis and formulation
- Scientist PhD in analytical, organic chemistry or a related discipline with minimum of 1 year of direct experience in oligonucleotide analysis and formulation
- Principal Research Associate MS in analytical, organic chemistry or a related discipline with minimum of 8 years of direct experience in oligonucleotide analysis and formulation
- Experience in the biotechnology and / or pharmaceutical industry is preferred, with direct experience with (semi)automated instruments.
- Strong method development skills including experience with liquid chromatography, capillary electrophoresis and mass spectrometry techniques.
- Proficiency with Chromeleon, Xcalibur and Biopharma Finder is preferred.
- Experience with managing project teams in a biotechnology organization is preferred.
- A history of authoring publications and / or study reports.
- A deep commitment to working as part of teams to deliver breakthrough medicines.
- Excellent communication, organization, and time management skills and ability to work both independently and collaboratively.
IND 005-010
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