Overview
The medicinal chemistry team within the Center for Drug Discovery supports client needs by conducting hit-to-lead and lead optimization.
We integrate medicinal chemistry into larger projects focused on drug discovery and development, including computational chemistry, in vitro assay development and HTS screening, in vivo behavioral pharmacology, ADME / PK bioanalytics, and regulatory support.
We have an immediate need for a Medicinal Chemist to join an exciting and growing team. Ideally, you will be a highly motivated and organized individual who desires a role involved in the synthesis of monomers, building blocks, peptides and oligonucleotides as ligands for various biological targets including kinases, G protein-coupled receptors, ion channels, and antimicrobial targets.
At RTI, you will be provided the opportunity to conduct meaningful work in a collaborative, cross functional environment.
We are focused on your career development and provide a generous benefits package that includes tuition reimbursement, parental leave, paid time off, medical / dental, and 401K.
This position is a two-year term assignment with potential for annual renewal.
Responsibilities
- Assist with experimental design.
- Perform compound synthesis independently or as a member of a team.
- Ensure proper execution of studies and record-keeping.
- Perform data analyses and prepare manuscripts for publication.
- Attend conferences to present novel research findings.
- Assist with grant applications and laboratory management.
- Train junior investigators and technicians as needed.
- Review literature and patents to retrieve scientific information.
- Other duties as assigned by PI.
Qualifications
Ph.D. in synthetic or medicinal chemistry or a related discipline field of study
Demonstrated experience across a diverse range of chemical reactions.
- Highly desirable to possess experience in solid-phase peptide and oligonucleotide synthesis.
- Proficiency in utilizing RP-HPLC, LC / MS, NMR, and chiral separation techniques.
- Highly desirable to have experience in cell cultures and / or biological assays.
- Desirable to possess knowledge of basic computational techniques.
- Adept at working independently in a fast-paced environment.
- Proficient in English.
RTI is committed to Lead Forward. We innovate, develop talent, collaborate, communicate, think globally, act strategically, and engage inclusively.
If that aligns with your values, we would like to hear from you. Join us and experience the RTI Difference.
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