Postdoctoral Fellow

Position Description :

Purpose : An NIH-funded postdoctoral fellowship in the laboratory of Dr. William Drobyski in the Departments of Medicine and Microbiology and Immunology at the Medical College of Wisconsin that is focused on transplantation immunology and immuno oncology.

We have ongoing projects focused on the immunobiology of allogeneic bone marrow transplantation, the pathophysiology of graft versus host disease (GVHD), and cancer immunotherapy.

Specific areas of interest include inflammatory cytokine networks that contribute to GVHD, inflammatory cytokine signaling and regulatory pathways that impact the development of tolerance, modulate anti-leukemic responses, and induce pathological damage particularly within select organs such as the gastrointestinal tract and central nervous system, and the harnessing and optimizing of T cell function for cancer immunotherapy using genetically modified mouse models, flow cytometry, q-PCR, RNA-seq, western blot, single cell RNA seq, bioinformatics, and other immunological techniques.

We also have a strong record of conducting translational clinical trials in which a post-doctoral fellow could contribute and participate. Recent publications include

Journal of Clinical Investigation 2016; 126 : 3541-3555,

JCI Insight 2017; 2(14) : 93726,

Haematologica 2018; 103(4) : 717-727,

Blood 2018; 132(4) : 435-447,

Nature Communications 2018; 9(1) : 5037;

Blood 2020; 135(8) : 568-581,

Blood 2021; 137(9) : 1241-1255,

Blood Advances 2022; 6(9) : 2791-2803; and

Haematologica 2023; 108(1) : 250-256.

Characteristics of a postdoctoral appointment :

It is expected that postdocs at MCW, with the assistance of their supervisor, will :

• Transition to career independence through the development of professional skills that enable the postdoc to actively pursue a career of his / her own choosing.
• Be supervised by at least one senior scholar who actively promotes the postdoc's professional development.
• Establish an individual development plan (IDP) that incorporates equally the postdoc's career and training goals and the mentor's research goals.
• Pursue basic, clinical, or translational projects so long as effort is focused primarily on research.
• Publish results of the postdoc's research and scholarship during their appointment.
• The postdoctoral appointment is temporary by nature, the aggregate amount of time spent as a postdoc is recommended to not exceed five years (not including family medical leave or maternity / paternity leave).
• As postdocs are important members of the host institution's community, appropriate levels of compensation, health care, and other benefits commensurate with their essential status should be afforded, independent of the postdoc's source of funding.

Primary Functions

• Plan, design and execute complex research studies, procedures and protocols pertaining to bone marrow transplantation.
• Participate in discovery projects.
• Coordinate research study activities; lead and manage projects.
• Oversee organization, synthesis and analysis of data and findings.
• Prepare scientific reports, outcome findings and scientific manuscripts.
• Participate in meetings with principle investigator and research staff in which you will evaluate / interpret the validity of data, develop methodologies, and design and evaluate lab procedures.
• Maintain supplies, may require negotiation with vendors, and track purchase orders.
• May oversee the work of laboratory personnel including training and development as well as daily work direction, delegation and establishing priorities.
• Assist in training students and more junior member of the laboratory. Perform other duties as assigned.

Preferred Schedule :

Full-time role with expectations for coverage during core business hours and flexibility required as necessary to accommodate business needs.

Position Requirements :

Knowledge - Skills - Abilities

Required knowledge : biology, chemistry, mathematics, statistics, documentation, records management, data utilization, complex problem solving, critical thinking, resource management, and writing skills

Skills and abilities :

• Must be adept at designing and performing experiments and interpreting data.
• Excellent communication skills

Organizational Structure :

Building : MACC Fund Research Center, 6061

Department : Medicine

Division : Hematology and Oncology

Reports to (Title) : Principal Investigator - Dr. William Drobyski and BOC - Kim Macik

Collaborates with (Titles) : Research staff and students.

Specifications

Minimum Required Education : PhD in Immunology, Microbiology or related field

Minimum Required Experience : Research skills include immunology, molecular and cellular biology techniques

Preferred Experience : Immunology, including mouse models, flow cytometry and / or molecular biology

Why MCW?

• Outstanding Healthcare Coverage, including but not limited to Health, Vision, and Dental. Along with Flexible Spending options
• 403B Retirement Package
• Competitive Vacation and Paid Holidays offered
• Tuition Reimbursement
• Paid Parental Leave
• On campus Fitness Facility, offering onsite classes.
• Additional discounted rates on items such as : Select cell phone plans, local fitness facilities, Milwaukee recreation and entertainment etc.

For a full list of positions see : www.mcw.edu / careers

For a brief overview of our benefits see : https : / / www.mcw.edu / departments / human-resources / benefits

Eastern Wisconsin is a vibrant, diverse metropolitan area. MCW is intent on attracting, developing, and retaining a diverse workforce and faculty body that reflects the community we serve.

We value diversity of backgrounds, experience, thought, and perspectives to advance excellence in science and medicine. MCW is a welcoming campus community with a strong culture of collaboration, partnership, and engagement with our surrounding community .

For more information, please visit our institutional website at https : / / www.mcw.edu / departments / office-of-diversity-and-inclusion .

LI-AC1

MCW as an Equal Opportunity Employer and Commitment to Non-Discrimination

The Medical College of Wisconsin (MCW) is an Equal Opportunity Employer. We are committed to fostering a diverse community of outstanding faculty, staff, and students, as well as ensuring equal educational opportunity, employment, and access to services, programs, and activities, without regard to an individual's race, color, national origin, religion, age, disability, sex, gender identity / expression, sexual orientation, marital status, pregnancy, predisposing genetic characteristic, or military status.

Employees, students, applicants or other members of the MCW community (including but not limited to vendors, visitors, and guests) may not be subjected to harassment that is prohibited by law or treated adversely or retaliated against based upon a protected characteristic.