Senior Scientist, Biostatistics

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Job Description

Our Research Scientists are our Inventors. We identify and target steps in disease mechanisms or pathways that could be inhibited or enhanced.

Our goal is to isolate a compound that is effective against a disease target. Using innovative thinking, state-of-the-art facilities and robust scientific methodology we collaborate to discover the next medical breakthrough.

This position is for a Statistician who will contribute to identifying, developing and validating oncology biomarkers that can be used to support our company's oncology programs, and / or to serve as companion diagnostics.

The position is also responsible for supporting regulatory filing related to oncology biomarkers. This position requires solid statistical knowledge, excellent communication skills and strong programming capability.

A successful applicant is expected to be self-motivated and innovative.

Primary responsibilities :

• Lead translational oncology biomarker statistical analysis plan development, statistical analyses, discussion, results sharing and publication.
• Provides statistical support for companion diagnostics development including cut point selection and bridging analysis for regulatory approval.
• Interacts with Discovery and Translational, Clinical, Regulatory, Statistical Programming, and other Research Laboratories scientists in analyzing oncology biomarker and clinical data.

Primary activities :

• Serves as the lead statistician to support biomarker research for early oncology programs or late-stage oncology indications.
• Develops scientific statistical analysis plans for oncology biomarker projects.
• Analyzes biomarker and clinical data and interprets the results.
• Prepares oral presentations and written reports to effectively communicate analysis results to multidisciplinary teams.
• Identifies technical or other potential problems arising in the biomarker projects, proposes solutions and carries them out.
• Participates in biomarker related meetings to gain high-level understandings of the projects, and to ensure the quality of the data and the analysis.
• Conducts research for innovative statistical methods and their applications in biomarker projects.

Position Qualifications :

Education Minimum Requirement :

• A PhD degree in statistics / biostatistics or related areas, or
• A Master’s degree in statistics / biostatistics with at least 4 years of relevant work experience.

Required Experience and Skills :

• Solid knowledge of statistical analysis methodologies especially in Bayesian inference (including hierarchical modeling), logistic regression, and survival analysis.
• Solid knowledge of statistical and data processing software, especially R language.
• Strong oral and written communication skills.
• Ability to function well both independently and collaboratively.
• Strong project management skills.
• Demonstrated interest in statistical methodology research and in the application of novel methods to real-world data analysis problems.
• Demonstrated ability to learn, be proactive and motivated, and consistently focus on details and execution.
• Ability to collaborate with scientists and work on multidisciplinary teams.

Preferred Experience and Skills :

• Knowledge and experiences in Bayesian modeling and analysis with jags, stan or customized MCMC procedure using R is highly desired.
• A specialization and relevant job experience in oncology.
• An understanding of the process to generate biomarkers, and the biology of disease and immunology.

Salary and Benefits :

Expected US salary range : $111,400.00 - $175,300.00. Available benefits include bonus eligibility, long term incentive if applicable, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days.

Employee Status : Regular

Relocation : Domestic

VISA Sponsorship : Yes

Travel Requirements : 10%

Flexible Work Arrangements : Hybrid

Job Posting End Date : 10 / 25 / 2024

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