Position Title : Research Scientist
Location : South San Francisco, CA 94080
Duration : 12 months contract (with possible extension)
Job Summary / Responsibilities :
This is a Bio-conjugation Scientist role with MRL SSF Discovery Chemistry group.
Client is currently seeking highly motivated and exceptional a Bio-conjugation Scientist for positions within the Discovery Chemistry Department located at our South San Francisco, CA site.
- The successful candidate will join multidisciplinary, highly collaborative discovery teams to invent Client medicines by applying optimized conjugation protocols, analytical techniques, and data analysis to synthesize drug candidates and intermediates.
- Successful candidates must have excellent interpersonal, collaboration, and communication skills in a team environment.
- Additionally, it is expected that the successful candidate will learn quickly through on-the-job training to become increasingly skilled and independent in reaction setup, route design and optimization.
Specific responsibilities will include :
- Perform bioconjugations of linker-payload combinations to antibodies with emphasis on in-house established methods
- Selection and application of appropriate purification techniques for biologics (i.e., SEC, hydrophobic interaction chromatography, ion exchange chromatography)
- Acquisition and interpretation of analytical data such as LC / MS.
Qualifications :
This is a Bio-conjugation Scientist role, so please advertise it as per this title to get the relevant resumes and candidates' applications.
Education Requirement :
Minimum qualifications include a B.S. / M.S / PHD in chemistry, biochemistry, or related field, with industrial or academic experience.
Experience and Skills Required :
- Hands on experience with c onjugation, purification and characterization of antibody drug conjugates , and experience using analytical techniques / instrumentation, including chromatographic techniques such as HIC (Hydrophobic Interaction Chromatography) and RP (Reverse Phase), SEC, SDS-PAGE, UV Vis.
- Nice to have skills : Biologics analytic experience, purification techniques.
- Must have : Bio-conjugation experience, protein biochemistry and Chemistry background.
- Personality : Team player, Adheres to timeline, Communicative and collaborative.
Note : Onsite, 100% Lab based role. Possibility of extension.