Sr. Research Associate I, Pivotal Purification Process Development

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe.

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Job Description

At a future date this position will relocate to the corporate HQ in Foster City, CA.

Gilead Sciences is seeking a Sr Research Associate I with experience in protein purification process development to support operations at our biologics development.

Essential Duties and Job Functions :

• Plan and execute assigned experiments that support Process Development activities and project goals.
• Select appropriate methods and techniques for performing experiments.
• Develop skills in data analysis and interpreting experiment outcomes including the ability to evaluate data quality and recognize anomalous results.
• Recommend alternatives, research new methods and techniques and proactively seek out senior personnel to discuss potential solutions to problems.
• Participate in group meetings and present results, data interpretation and conclusions.
• Demonstrate strong verbal communication and interpersonal skills including the ability to explain processes used to achieve results of assigned tasks.
• Work with team oriented, collaborative and problem-solving mindset.
• Always work with safety in mind.

Knowledge, Experience and Skills :

• Preferred degree in Chemical / Biochemical Engineering, Biochemistry, Chemistry or a related scientific discipline.
• Prior experience in biologics purification, with an emphasis on affinity, IEX, and HIC.
• Prior experience in analytical operations : SEC / HPLC, CE (R / NR), HCP testing is beneficial, but not required.
• Knowledge of cGMPs, technology transfer, and scaling up bioprocesses.
• Must be able to work effectively in cross-functional teams.
• Must demonstrate excellent technical writing skills.
• Working understanding of downstream process development including centrifugation, normal and tangential flow filtration, chromatography operations, and virus clearance.

The ability to demonstrate hands on experience in several of these areas is expected. Experience with multiple modalities (mAbs, bispecifics, fusion and antibody drug conjugates, virus particles) produced in microbial and mammalian expression systems is a plus.

• Ability to work effectively within the purification team to help design and execute experiments supporting process definition, optimization, and characterization with an increasing level of independence.
• Ability to collaborate with Technical Operations during technology transfer from process development to GMP manufacturing, including serving as a process development representative during purification operations, providing technical troubleshooting and identifying opportunities for future process and equipment improvements.

The candidate will also contribute to the preparation of regulatory filings and process validation and characterization reports.

Ability to effectively communicate ideas, project goals and results and should have the ability to proactively identify issues and suggest solutions in a collaborative, multidisciplinary environment.

This is a highly collaborative environment where willingness and ability to communicate and work effectively with individuals across various teams is essential.

Self-motivated, organized, and enjoy scientific investigation and thinking. The candidate will monitor and contribute to external literature and scientific conferences.

Basic Qualifications :

• BS degree in a relevant scientific discipline and 2+ years of relevant experience; OR
• MS degree in a relevant scientific discipline and 0+ years of relevant experience.

The salary range for this position is : $84,405.00 - $109,230.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location.

These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package.

Benefits include company-sponsored medical, dental, vision, and life insurance plans.

For additional benefits information, visit : https : / / www.gilead.com / careers / compensation-benefits-and-wellbeing

As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws.

In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact [email protected] for assistance.

For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.

Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

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