Senior Scientist II, Pathology

AbbVie
Waltham, MA, US
Full-time

Job Description

Job Description

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow.

We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio.

For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.

Job Description

We are seeking a highly motivated individual to work within the Precision Medicine Pathology Group to develop and implement tissue-based assays to support drug development in oncology and other therapeutic areas.

The Senior Scientist will drive the design, implementation and analysis of diagnostic and translational tissue-based biomarkers & participate in target discovery and validation projects.

This role will accomplish this by conducting histopathological evaluation as well as computer-based image analysis of IHC and other tissue-based assays, as well as by providing technical / scientific leadership in these areas.

The successful candidate will have the opportunity to work in a highly collaborative environment and will participate as a member of multidisciplinary, cross-functional discovery, translational, and development project teams.

Major Responsibilities

  • Design, validate, and implement histochemical, IHC, and IF staining using Leica Autostainer XL, Ventana Discovery ULTRA, and Leica BOND RX platform.
  • Perform routine histological procedures including tissue accessioning, gross-dissection, tissue processing, embedding, sectioning, staining and image capture of frozen and FFPE tissues
  • Perform image capture (whole slide scanning), data entry and organization
  • Perform image analysis using HALO and Visiopharm technologies
  • Generate data and present findings to relevant project teams in departmental and cross-functional meetings
  • Lead and maintain external vendor collaborations and relationships
  • Train staff in image analysis, quantification, and spacial biology techniques
  • Evaluate and bring in new and innovative image analysis and spacial biology tools and techniques

Qualifications

Bachelor’s Degree in Science related field with 15+ years of related work; Master’s Degree Science with 10+ years of related work;

PhD in Science or related field* with 4+ years of related work experience. (*Cancer Biology, Physiology, Cell Biology or a related field)

  • Strong familiarity with the principles of tissue microscopic anatomy / histology
  • Experience working in collaboration with trained pathologists
  • Hands-on experience with development of immunohistochemistry (IHC) and other tissue-based assays including immunofluorescence (IF) multiplexing and in situ hybridization (ISH) preferred
  • Expertise in quantitative image analysis software and its application to IHC and other tissue-based staining modalities
  • Excellent verbal communication skills are required including the demonstrated ability to effectively and clearly summarize results for presentation and report generation

Strong motivation, attention to detail, ability to think independently and fully integrate into a high achieving team environment

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law :

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position.

Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range.

This range may be modified in the future.

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical / dental / vision insurance and 401(k) to eligible employees.

This job is eligible to participate in our short-term incentive programs.

This job is eligible to participate in our long-term incentive programs

Note : No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.

It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

US & Puerto Rico only - to learn more, visit https : / / www.abbvie.com / join -us / equal-employment-opportunity-employer.html

30+ days ago
Related jobs
Promoted
AbbVie
Waltham, Massachusetts

The Senior Scientist will drive the design, implementation and analysis of diagnostic and translational tissue-based biomarkers & participate in target discovery and validation projects. We are seeking a highly motivated individual to work within the Precision Medicine Pathology Group to develop...

Promoted
AbbVie
Waltham, Massachusetts

The Senior Scientist will drive the design, implementation and analysis of diagnostic and translational tissue-based biomarkers & participate in target discovery and validation projects. We are seeking a highly motivated individual to work within the Precision Medicine Pathology Group to develop...

Promoted
Novartis Group Companies
Cambridge, Massachusetts

Internal Title: Senior Scientist I. OPB is seeking a motivated Senior Scientist to develop tissue-based biomarker assays (e. Within OTR, the Oncology Pathology and Biomarkers (OPB) group uses tissue-based, cell-based and soluble protein assays to understand target epidemiology and biology, mechanism...

Promoted
AbbVie
Cambridge, Massachusetts

AbbVie's MPDD organization is seeking a highly motivated, talented, and creative scientist with expertise and some experience in pharmaceutical sciences and drug delivery for a Senior Scientist II position. Senior Scientist II typically requires Bachelors, Masters, or Ph. From candidate selection th...

Promoted
Novartis Group Companies
Cambridge, Massachusetts

Senior Scientist II level and $118,400 and $177,600 at the Principal Scientist I level however, while salary ranges are effective from 1/1/24 through 12/31/24, fluctuations in the job market may necessitate adjustments to pay ranges during this period. The Pharmacokinetic Sciences (PKS) Department w...

Promoted
AbbVie
Cambridge, Massachusetts

AbbVie is seeking a highly motivated, collaborative scientist with a proven track record in physicochemical characterization and application of drug delivery approaches in preclinical development of small molecule and/or biologics candidates. ...

Promoted
Novartis Group Companies
Cambridge, Massachusetts

The final level & title of the offer role would be determined by the hiring team based on the skills; experience & capabilities required to perform the role at the level the role has been offered (Senior Scientist I /Senior Scientist II). The Senior Scientist, Immunogenicity and Mechanistic Immunolo...

Promoted
Deciphera Pharmaceuticals
Waltham, Massachusetts

Deciphera, a member of ONO, is a biopharmaceutical company focused on discovering, developing and commercializing important new medicines to improve the lives of people with cancer.We are leveraging our proprietary switch-control kinase inhibitor platform and deep expertise in kinase biology to deve...

Promoted
AbbVie
Cambridge, Massachusetts

AbbVie is seeking a highly motivated, collaborative scientist with a proven track record in physicochemical characterization and application of drug delivery approaches in preclinical development of small molecule and/or biologics candidates. ...

Promoted
Beacon Hill Life Sciences - Boston
Cambridge, Massachusetts

This Senior Scientist II/III level role requires working closely with the wider multidiscplinary research team to discover new small molecule therapeutics for the treatment of cancer. This position will report to a Senior Principal Investigator, Biological Sciences, and work onsite at our research f...