We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place.
To fully realize Pfizer’s purpose Breakthroughs that change patients’ lives we have established a clear set of expectations regarding what we need to achieve for patients and how we will go about achieving those goals.
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues.
Why Patients Need You
Find out more about this role by reading the information below, then apply to be considered.
At Pfizer we deliver breakthroughs that change patients’ lives with the mission to outdo cancer. The ADC (Antibody-Drug-Conjugate) chemistry team plays a vital role in this mission through discovering and advancing novel ADC linker / payload technologies for targeted cancer therapies.
We are looking for a highly motivated, creative, and collaborative researcher to join our ADC chemistry team in a lab-based role in Bothell, Washington, to support novel ADC technology development.
The successful candidate will participate in research projects involving the design and synthesis of novel ADC payloads and drug linkers.
Activities may also include coordinating or performing biological assays to understand drug linker and ADC properties.
Key Responsibilities
- Design and perform multi-step syntheses for novel ADC payloads, drug linkers, and key intermediates.
- Work independently to develop, troubleshoot and optimize synthetic routes, including modular routes for rapid analog generation and efficient scalable routes for early-stage drug candidates.
- Operate in a variety of analytical instruments and technologies including HPLC, LC / MS, NMR to enable structural determination and purity assessment.
- Work effectively in both independent and highly collaborative settings.
- Analyze and accurately record data using Electronic Laboratory Notebooks.
- Actively participate in discussions and present results in the form of written reports and oral presentations.
- Adhere to all company safety, scientific record keeping, and compliance requirements.
Qualifications
- Master’s degree with 4+ years or bachelor’s degree with 6+ years industrial experience as a synthetic organic chemist.
- Deep understanding of organic functional groups, reaction mechanisms, and reactivity.
- Ability to use chemistry and literature / patent searching software to plan and execute synthetic strategies.
- Proven record as a synthetic organic chemist familiar with a wide range of reaction types and having demonstrated multi-step synthesis, purification, and characterization of organic compounds, especially using NMR and mass spectroscopy.
- Strong interpersonal skills and effective written / verbal communication.
- Ability to work effectively in multi-disciplinary teams, learn new skills, and proactively solve problems.
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