Read on to find out what you will need to succeed in this position, including skills, qualifications, and experience.
SUMMARY
Cartesian Therapeutics is reimagining Cell Therapies with promising breakthroughs to help patients with autoimmune diseases.
We are looking for a Principal Scientist that will be responsible for process development / optimization, and GMP manufacturing support to facilitate Phase I & II enabling activities.
We are interested in talented scientists with potential for growth. If your experience does not meet all the requirements but you can demonstrate that you can quickly learn and adapt, we encourage you to apply.
RESPONSIBILITIES :
- Independently design, develop, and execute experiments for bioprocess development (CAR-T cell therapy), optimization, and characterization.
- Coordinate with internal & external partners to manage sample testing, critical raw material manufacturing etc.
- Serve as bioprocess SME that provides technical oversight in support of IND filling and to ensure that clinical manufacturing is successfully executed per schedule.
- Supports initiatives for new technology development and continuous improvement projects.
- Independently author technical reports of studies, protocols, SOP and risk assessments to enable technology transfer, manufacturing and IND activities.
- Other duties as assigned.
QUALIFICATIONS :
- PhD in Chemical Engineering, Biochemistry, Cell Biology or related degree.
- 7 years of relevant industry experience.
- Experience with a variety of mammalian cell culture bioreactor technologies, including perfusion (Upstream process).
- Excellent team player with good communication skills.
- Indirect and direct leadership in a setting with multi-functional teams.
PREFERRED QUALIFICATIONS :
- Working knowledge of statistics and experience with Design of Engineering (DoE) approach.
- Experience with T- cells or other types of immune cell selection, expansion and culture.
- Experience with flow cytometry and ELISA assays.
CARTESIAN is an Equal Opportunity Employer and is committed to fostering an environment in which all employees are treated fairly without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, ancestry, disability, marital status, genetic information, military status, or any other characteristic protected under applicable law.
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