Translational Medicine Sr. Principal Scientist Neurology

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Summary / Scope

Reporting to Senior Scientific Director Translational Medicine, the TM Sr. Principal Scientist will be part of the late stage TM group.

The individual will be responsible for TM and clinical biomarker activities to support drug development programs in multiple diseases in neurology and neuropsychiatry.

This individual will have the opportunity to assume biomarker lead responsibilities, such as serving as biomarker representative on study teams, setting up biomarker plans for individual trials and ensuring appropriate collection and timely analysis and reporting of final biomarker data.

The individual will also be responsible for answering key TM questions related to the assigned assets and diseases via collaboration with TM laboratory team and / or academic thought leaders.

The successful candidate will have prior therapeutic area and late development clinical experience in biotech / pharma organizations interacting with project teams, clinical research physicians, statisticians, computational biologists, contract research organizations and translational scientists to deliver science that supports the development of medicines to patients in need.

Responsibilities will include, but are not limited to, the following :

• Designs and implements program-specific biomarker / translational plans, responsible for aiding in creation of clinical protocols, SAPs, SOWs, lab manual, and interfacing with CRO for execution of services, in conjunction with Biospecimen Operations and Procurement.
• Determines appropriate assays and vendors for clinical biomarkers, and manages outsourcing of biomarker assay development and validation partnering with Translational Sciences colleagues when applicable
• Manages clinical biomarker data delivery and analysis and associated timelines by working with relevant internal functions and CROs;
• Prepares and delivers internal and external translational / biomarker presentations
• Maintains timelines for biomarker data related publication through interaction with Medical Communications and Publication team as needed
• Keeps up-to-date on relevant scientific / technical literature in order to applying external knowledge to internal research programs as appropriate and acts as a subject-matter expert within the team to critically evaluate the literature regarding the asset and disease biology
• Works with TM laboratory scientists and academic TLs to address nonclinical translational questions
• Participates in post-hoc biomarker analysis and publication efforts
• Supports regulatory submissions and regulatory interactions as needed

Skills / Knowledge Required

• Understanding of late stage drug development
• Experience in activities required for and related to clinical trial initiation, maintenance and completion
• Experience in interacting with CROs and TLs to manage projects and timelines
• Proven scientific / leadership expertise (working in teams, mentoring people, managing projects)
• Accountable for timelines and deliverables
• Prioritizes risks and implements contingency plans
• Communicates regularly; prepares and delivers presentations within the department, to governance and senior leadership bodies, and externally as requested
• Recognizes cross-functional issues and communicates within the larger organization. Provides expert guidance to multi-disciplinary teams and senior management.

Has a track record of delivering results, driving continuous improvements, and building effective cross-functional networks.

• Ability to prioritize and manage time efficiently
• Strong verbal and written communication skills
• Accurate and detailed record keeping
• Excellent organizational skills

Basic Qualifications :

• Bachelor’s Degree10+ years of academic and / or industry experience
• Master’s Degree8+ years of academic and / or industry experience
• Ph.D. or equivalent advanced degree in the Life Sciences 6+ years of academic and / or industry experience
• 2+ years of leadership experience

Preferred Qualifications :

Ph.D. in neuroscience or related field 8+ years of academic / biotech experienceMinimum 3 years of clinical biomarker experience

Functional / Scientific / Technical Skills :

• Contributing to research program and business.
• Subject matter leader.
• Broad knowledge of multiple functional technologies.
• In-depth understanding of function as it relates to project.
• Functional area expert with skills, theoretical knowledge and experience to apply scientific direction and approach to projects and problems.

Tasks and Responsibilities :

• Completes technical assignments by designing, executing and interpreting complex experiments.
• Recommends department level strategic decisions.
• May lead scientifically on cross functional assignments.
• Manages and / or coordinates workflow on projects.
• Apply diverse scientific knowledge to assignments.
• Development of research tools.
• Interpret results.

Discretion / Latitude :

• Helps design operational strategies consistent with department goals.
• Provides input and makes recommendations to research strategies.

Creativity and Problem Solving :

• Identify & solve multi-faceted challenges.
• Recognizes problems and is able to recommend and develop appropriate solutions from prior experience, literature, or collaboration.
• Identify risks.
• Contributes ideas and develops / presents a scientific case (or position) inside and outside department / group.

Teamwork and Influence :

• Communicates with cross functional team.
• Directly impacts the achievement of workgroup / team goals.
• Represents workgroup / team or department on multi-disciplinary or cross functional teams.
• Work across departments.

Organizational Impact :

• Direct impact on departmental performance.
• Impact is achieved by driving team efforts.
• Able to conceptualize broad impact of research programs and personal activities in terms of site.

Behavioral Competencies :

• Champions change
• Leads courageously
• Networking
• Provides directions
• Structuring and staffing
• Thinks strategically

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as Transforming patients’ lives through science™ , every BMS employee plays an integral role in work that goes far beyond ordinary.

Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs.

The occupancy type that you are assigned is determined by the nature and responsibilities of your role :

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility.

For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture.

For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations / adjustments and ongoing support in their roles.

Applicants can request a reasonable workplace accommodation / adjustment prior to accepting a job offer. If you require reasonable accommodations / adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to .

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BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

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