Senior Hemocompatibility Engineer

Job Description

Job Description

BrioHealth Solutions Inc. is seeking a Senior Hemocompatibility Engineer to lead research and development efforts related to the hemocompatibility of Left Ventricular Assist Devices (LVAS).

As a key member of our team, you will play a crucial role in advancing LVAS technology, conducting meaningful research, improving patient outcomes, and ensuring device safety.

Your expertise in blood-device interactions and biocompatibility will drive innovation and guide our product development.

Key Responsibilities :

• Conduct in-depth studies on the hemocompatibility of LVADs, including thrombosis, bleeding events, and anticoagulation strategies.
• Collaborate with cross-functional teams (engineering, clinical, regulatory) to design and execute experiments, analyze data, and interpret results.
• Investigate novel materials, coatings, and surface modifications to enhance LVAD biocompatibility.
• Evaluate the impact of LVAD design features on blood flow dynamics and cellular responses.
• Develop and validate assays to assess hemocompatibility, including platelet activation, coagulation, and inflammatory markers.
• Stay abreast of industry trends, scientific literature, and regulatory guidelines related to LVAD hemocompatibility.
• Present findings at conferences, contribute to publications, and participate in scientific discussions.
• Stay updated with cutting-edge technologies and laboratory techniques.
• Complete comprehensive documentation associated with project deliverables.
• Integrate academic and experiential knowledge to develop innovative solutions.
• Communicate and influence effectively across a multi-site, global organization.
• Act as a mentor to others in the organization.

Requirements :

• Bachelor's Degree, Master’s preferred in applicable discipline : Chemistry, Biology, Biomedical Engineering, etc.
• Good understanding of and experience of applying the principles, theories, and concepts in biocompatibility per ISO 10993
• 8+ years of experience in Research and Development, or a Master’s Degree and 5+ years of related experience.
• Strong knowledge of blood-biomaterial interactions, thrombosis, and anticoagulation.
• Proficiency in experimental design, statistical analysis, and data interpretation.
• Experience with relevant laboratory techniques (flow cytometry, ELISA, etc.).
• Proficiency in the FDA Quality System Regulation and experience in a regulated industry preferred.
• Ability to effectively communicate technical concepts to diverse stakeholders.
• Good understanding of the principles, theories, and concepts in biocompatibility testing per ISO-10993 would be beneficial
• Experience with histopathological evaluation of explanted devices would be beneficial
• Positive outlook, innovative thinking, and self-sufficiency in problem-solving.
• This position is in Burlington, MA

About BrioHealth Solutions

We are a global team of like-minded Med-Tech professionals focused on patient centric solutions in a collaborative environment leading to excellent outcomes.

We have developed an advanced and unique heart failure therapy technology in the BrioVAD® Left Ventricular Assist System (LVAS).

We are introducing the BrioVAD LVAS to Heart Failure clinicians for use with the large number of indicated and untreated patients who could benefit from chronic mechanical circulatory support.

The initiation of our INNOVATE™ Trial in the US is only the beginning. We are building a team to develop advanced technology intended to further improve patient outcomes, increase therapy acceptance, and enabling chronic MCS therapy to be accessible to more patients across the globe.