Vivo Animal Research Investigator - NCWR

Position Details

Req ID : req16870

req16870

Position Title :

Vivo Animal Research Investigator - NCWR

Position Type : Staff Full-Time

Staff Full-Time

Position Number : GS9182

GS9182

OSU Campus :

Tulsa - Center for Health Sciences / OSU Medicine

Department :

Center for Wellness and Recovery

Location Address :

1111 West 17th Street

Tulsa , Oklahoma, 74107

United States

Hiring Supervisor : Hiring Range :

Hiring Range :

Contingent upon available funding) :

Commensurate with education and experience

Work Schedule :

Typically 8 hrs / day, 5 days / week

Faculty Appt Period :

Job Summary :

THIS POSITION IS GRANT FUNDED.

Job Summary :

TheNCWR is currently expanding its in vivo research team with openings atall levels. Significant hands-onwork in the animal vivarium is expected from all candidates.

For the moresenior levels, strategic and managerial duties are also expected.

Additional Responsibilities :

Familiarity and / or willingness to learn and apply specialized techniques such as DREADD, imaging methods, microscopic techniques, etc.

to on-going research at the NCWR.

• Be willing to learn new behavioral techniques and animal models and apply them independently or as part of a team.
• Familiarity with software related to behavioral testing and data collection.
• Attention to detail in record-keeping and lab safety including the use of controlled substances in experiments.

The National Center for Wellness and Recovery(NCWR) at Oklahoma State University Center for Health Sciences (OSU-CHS) waspublicly launched in 2017 with a mission to inspire hope for people sufferingwith chronic pain and substance use disorders through treatment and research.

The NCWR was the recipient of nearly $200M from Purdue Pharma as part of theirsettlement with Oklahoma and the funds are being leveraged to advance thescience of addiction and pain.

Currentlywe are making multi-million-dollar investments in neuroscience research anddrug discovery competencies including medicinal chemistry, molecular biology,animal models, and pharmacology.

We are uniquely organized within OSU-CHS toallow researchers to be highly focused on the urgent mission of the NCWR as apriority.

NCWR researchers and clinicians are expected to seek ways to rapidlytranslate new mechanism-based treatment modalities to patient care.

The NCWR iscurrently building a $21M state-of-the-art animal facility, as well as a $50M, 30,000sq ft pharmaceutical research facility as part of a new medical district in downtownTulsa.

The NCWR endorses a culture of teaching, learning, and collaboration,thus creating opportunities for our people to grow in their careers throughdirect interactions on multidisciplinary teams with colleagues.

This is an opportunity to join a growing teamthat is focused on making a positive impact in the lives of those sufferingfrom addiction and / or chronic pain.

Environmental Hazard :

Possible exposure to hazardous material, hot and cold, blood borne pathogens.Exposure to rodents.

Physical Requirement :

Ability to lift and carry 20 pounds, stoop, reach, stand, walk, finger, grasp,feel, talk, hear, see, and perform repetitive motions with or withoutreasonable accommodations.

Special Instructions to Applicants

Education & Experience

Position Qualifications :

Requirements :

• Bachelors, Masters, or a PhD in Neuroscience, Pharmacology, or related field.
• In vivo animal research experience is required.
• Experience may include post-doctoral, academic and industry working in an animal laboratory
• A broad knowledge of animal anatomy,physiology, and biochemistry to help develop and support in vivo models toscreen therapeutics and devices being developed for various clinicalindications.

Skills, Proficiencies, and Knowledge :

• Experience in pre-clinical rodent models, for example, substance use disorders and pain, models of behavior including CPP, and anxiety, as well as physiological measures including respiration and GI motility.
• Excellent understanding of IACUC-related concepts and will be familiar in AAALAC standards for laboratory animal care and use.
• Design and perform experimental models related to pain and addiction behavior in rodents, including preparation of protocols and IACUC interactions.
• Provide input into new equipment purchases, set-up, and training as needed, necessary for NCWR to have a superior level of capabilities that support state-of the-art and flexible in vivo operations in neuroscience with emphasis on pain and addiction.
• Maintain the cleanliness and readiness of the equipment used by NCWR in the vivarium as needed.
• As needed, develop and validate behavioral models and methods that support NCWR’s multidisciplinary research projects and exploratory research.

This may include modification of known literature procedures or developing novel techniques.

Interact within multi-disciplinary research teams to establish screening tree criteria and test novel compounds in appropriate animal models for efficacy and side effects.

Various methods of dosing will be required.

Collaborate with NCWR analytical scientists to develop and apply in vivo pharmacokinetics and pharmacodynamics techniques.

This will include blood spot analysis, dosing, time-dependent blood sampling, and analysis.

• Write grant proposals, present at internal meetings, plan budgets, and supply technical content to patent applications and other documents.
• Supervise staff as needed, including PhDs and non-PhDs, including goal setting, mentoring, and allocating resources.

Preferred :

• Operational and interpretational knowledge of multiple animal models and equipment is highly preferred.
• Grant, publication, and report-writing experience.
• Industrial Experience.
• Experience in rodent behavior, dosing, sampling, documentation and report writing, PK / mass balance studies, as well as protocol reading and writing as needed.
• Experience with laboratory animal surgery and post-operative care, veterinary staff consultation, cursory necropsy and euthanasia.
30+ days ago